english

PhD in Advanced Biotechnology

2023/2024

Quality assurance

The UDC International Doctoral School (EIDUDC) is subject to an Internal Quality Assurance System (IQAS) which governs all UDC PhD programmes ratified by Royal Decree-Law 99/2011, in compliance with EU Standards and Guidelines for Quality Assurance in the EHEA. For more information, see documentation relating to the UDC International Doctoral School Internal Quality Assurance System (Regulations for the implementation and administration of the International Doctoral School SGIC for UDC PhD programmes ratified under RD 99/2011; International Doctoral School IQAS Manual; International Doctoral School IQASProcedures).

Guidelines for the monitoring and supervision of the student learning process and outcomes are established in the IQAS Procedures document. The bodies and mechanisms responsible for the coordination, evaluation and continuous improvement of the programme of study are as follows:

Academic Committee for PhD Programmes (CAPD): university body responsible for the academic coordination of PhD programmes and academic decisions regarding PhD degree and degree candidates. The CAPD establishes the guidelines and procedures for the programme coordinator and all individuals involved in the degree. A UDC coordinator is appointed for all UDC PhD programmes ratified under RD 99/2011, including inter-university programmes operated by partner universities.

EIDUDC Quality Assurance Committee (CGC): body responsible for formulating and monitoring the SGIC and PhD degree programmes. The CGC also fulfils an internal communication role within the EIDUDC in relation to its objectives, plans, programmes and responsibilities. An annual monitoring report is produced by the EIDUDC Permanent Committee, acting in the name of the CGC.

Learning outcomes

The International Doctoral School IQAS sets out the standards and indicators applied by Academic Committees in relation to UDC PhD programmes for the measurement and analysis of learning outcomes and academic standards.

These indicators include the number of doctoral theses defended, ‘International Doctorate’ certifications awarded, PhDs completed within the published time scale (3-4 years), PhDs awarded and PhDs abandoned, in addition to the average timescale for completion of the degree.

Quality assurance

To ensure that the title is developed in accordance with the verification report presented the center conducts an annual monitoring report in accordance with the procedures of the center IQAS and results. This report is reviewed by the ACSUG, external evaluation agency.

The outcome of this analysis will emerge corrective actions and improvement proposals that achieve the intended objectives and the improvement of the degree.

Committees

In order to ensure proper standards and quality at UDC, a specific academic management committee of the PhD programme will be established.

Veiga Barbazán, Maria del Carmen
Coordinadora
Becerra Fernández, Manuel
Secretario
Sanroman Braga, Maria Angeles
Vocal PDI
Gallego Veigas, Pedro Pablo
Vocal PDI
Doménech García, María Nieves
Vocal PDI

Program tracking facts

Period Value
Places offered
Number of places for new students entering PhD (IPD01)		 2022/2023 4
Demand
Number of applicants for PhD admission (IPD02)		 2022/2023 9
First-time enrollment
Number of first-time enrollment students in PhD (IPD03)		 2022/2023 7
First-time enrollment by adaptation
Number of first-time enrollment students in the program or students coming from other studies in extinction (IPD03.1)		 2022/2023 0
Total enrollment
Total number of students enrolled (IPD04)		 2022/2023 26
First-time enrollment coming from other universities
Ratio between the number of first-time enrolled students coming from other universities and the total number of first-time enrolled students in the program (IPD05)		 2022/2023 28.57
Percentage of foreign students
Ratio between the number of foreign students enrolled and the total number of students enrolled in the programme (IPD06)		 2022/2023 19.23
Percentage of first-time enrolled students who need training complements
Ratio between the number of students enrolled who need training complements and the total number of new students enrolled in the programme (IPD07)		 2022/2023 0
Percentage of full-time enrollees
Ratio between the number of students under full time status and the number of students enrolled in the programme (IPD08.1)		 2022/2023 73.08
Percentage of partial-time enrollees
Ratio between the number of students under half time status and the number of students enrolled in the programme (IPD08.2)		 2022/2023 0
Percentage of enrollees under mixed status
Ratio between the number of students under mixed status and the number of students enrolled in the programme (IPD08.3)		 2022/2023 26.92
Percentage of enrollees who carried out a stay passed by the CAPD (Outgoing)
Ratio between the number of students who carried out a stay as visiting researchers passed by the CAPD (outgoing students) and the total number of students enrolled in the programme (IPD09.1)		 2022/2023 n/a
Percentage of enrollees who carried out a stay passed by the CAPD at UDC (Incoming)
Number of students who carried out a stay as visiting researchers passed by the CAPD (incoming students) (IPD09.2)		 2022/2023 n/a
Percentage of enrollees with a grant or pre-doctoral contract
Ratio between the number of students with a grant or pre-doctoral contract and the number of students enrolled in the programme (IPD11)		 2022/2023 0
Percentage of theses defended by students who had several directors
Ratio between the number of theses defended by students of the programme who had several directors and the total number of defended theses in the programme (IPD14)		 2022/2023 100
Percentage of examination board members coming from an foreign institution
Ratio between the number of examination board members of thesis linked to the programme coming from an foreign institution and the total umber of examination board members of thesis linked to the programme (IPD17)		 2022/2023 33.33
Total number of defended thesis
Total number of defended thesis linked to the programme (IPD18.1)		 2022/2023 3
Percentage of defended thesis written by full-time students
Ratio between the total number of defended thesis written by students under full time status and the total number of defended theses in the programme (IPD18.2.1)		 2022/2023 33.33
Percentage of defended thesis written by partial-time students
Ratio between the total number of defended thesis written by students under partial time status and the total number of defended theses in the programme (IPD18.2.2)		 2022/2023 0
Percentage of defended thesis written by students under mixed status
Ratio between the total number of defended thesis written by students under mixed status and the total number of defended theses in the programme (IPD18.2.3)		 2022/2023 66.67
Total number of tesis written in Galician
Total number of defended thesis linked to the programme written in Galician (IPD18.3.1)		 2022/2023 0
Total number of tesis written in Spanish
Total number of defended thesis linked to the programme written in Spanish (IPD18.3.2)		 2022/2023 3
Total number of tesis written in other languages
Total number of defended thesis linked to the programme written in other languages (IPD18.3.3)		 2022/2023 0
Average duration of studies of full-time students
Average duration of studies for students under full time status who defended a thesis (in days) (IPD18.4.1)		 2022/2023 1,740
Average duration of studies of partial-time students
Average duration of studies for students under half time status who defended a thesis (in days) (IPD18.4.2)		 2022/2023 n/a
Average duration of studies of students under mixed time status
Average duration of studies for students under mixed time status who defended a thesis (in days) (IPD18.4.3)		 2022/2023 3,060
Success rate. Percentage of students who defended their theses without asking for an extension
Ratio between the number of doctoral students who defended their theses without asking for an extension and the total number of defended thesis linked to the programme (IPD18.5.1)		 2022/2023 0
Success rate. Percentage of students who defended their theses after asking for the first extension
Ratio between the number of doctoral students who defended their theses after asking for the first extension and the total number of defended thesis linked to the programme (IPD18.5.2)		 2022/2023 0
Success rate. Percentage of students who defended their theses after asking for the second extension
Ratio between the number of doctoral students who defended their theses after asking for the second extension and the total number of defended thesis linked to the programme (IPD18.5.3)		 2022/2023 100
Percentage of "cum laude" theses
Ratio between the number of defended theses linked to the programme with "Cum Laude" qualification and the total number of defended thesis linked to the programme (IPD18.6)		 2022/2023 100
Percentage of theses with International Component
Ratio between the number of defended theses linked to the programme with International Component and the total number of defended thesis linked to the programme (IPD18.7)		 2022/2023 66.67
Dropout rate
Ratio between the number of doctoral students who cause permanent withdrawal from the X course and the total number of doctoral students who could re-enroll in this programme. (IPDx21)		 2022/2023 0
Period Value
Places offered
Number of places for new students entering PhD (IPD01)		 2021/2022 4
Demand
Number of applicants for PhD admission (IPD02)		 2021/2022 8
First-time enrollment
Number of first-time enrollment students in PhD (IPD03)		 2021/2022 5
First-time enrollment by adaptation
Number of first-time enrollment students in the program or students coming from other studies in extinction (IPD03.1)		 2021/2022 0
Total enrollment
Total number of students enrolled (IPD04)		 2021/2022 22
First-time enrollment coming from other universities
Ratio between the number of first-time enrolled students coming from other universities and the total number of first-time enrolled students in the program (IPD05)		 2021/2022 20
Percentage of foreign students
Ratio between the number of foreign students enrolled and the total number of students enrolled in the programme (IPD06)		 2021/2022 31.82
Percentage of first-time enrolled students who need training complements
Ratio between the number of students enrolled who need training complements and the total number of new students enrolled in the programme (IPD07)		 2021/2022 0
Percentage of full-time enrollees
Ratio between the number of students under full time status and the number of students enrolled in the programme (IPD08.1)		 2021/2022 63.64
Percentage of partial-time enrollees
Ratio between the number of students under half time status and the number of students enrolled in the programme (IPD08.2)		 2021/2022 9.09
Percentage of enrollees under mixed status
Ratio between the number of students under mixed status and the number of students enrolled in the programme (IPD08.3)		 2021/2022 27.27
Percentage of enrollees who carried out a stay passed by the CAPD (Outgoing)
Ratio between the number of students who carried out a stay as visiting researchers passed by the CAPD (outgoing students) and the total number of students enrolled in the programme (IPD09.1)		 2021/2022 n/a
Percentage of enrollees who carried out a stay passed by the CAPD at UDC (Incoming)
Number of students who carried out a stay as visiting researchers passed by the CAPD (incoming students) (IPD09.2)		 2021/2022 n/a
Percentage of theses defended by students who had several directors
Ratio between the number of theses defended by students of the programme who had several directors and the total number of defended theses in the programme (IPD14)		 2021/2022 100
Percentage of examination board members coming from an foreign institution
Ratio between the number of examination board members of thesis linked to the programme coming from an foreign institution and the total umber of examination board members of thesis linked to the programme (IPD17)		 2021/2022 0
Total number of defended thesis
Total number of defended thesis linked to the programme (IPD18.1)		 2021/2022 1
Percentage of defended thesis written by full-time students
Ratio between the total number of defended thesis written by students under full time status and the total number of defended theses in the programme (IPD18.2.1)		 2021/2022 0
Percentage of defended thesis written by partial-time students
Ratio between the total number of defended thesis written by students under partial time status and the total number of defended theses in the programme (IPD18.2.2)		 2021/2022 0
Percentage of defended thesis written by students under mixed status
Ratio between the total number of defended thesis written by students under mixed status and the total number of defended theses in the programme (IPD18.2.3)		 2021/2022 100
Total number of tesis written in Galician
Total number of defended thesis linked to the programme written in Galician (IPD18.3.1)		 2021/2022 0
Total number of tesis written in Spanish
Total number of defended thesis linked to the programme written in Spanish (IPD18.3.2)		 2021/2022 1
Total number of tesis written in other languages
Total number of defended thesis linked to the programme written in other languages (IPD18.3.3)		 2021/2022 0
Average duration of studies of full-time students
Average duration of studies for students under full time status who defended a thesis (in days) (IPD18.4.1)		 2021/2022 n/a
Average duration of studies of partial-time students
Average duration of studies for students under half time status who defended a thesis (in days) (IPD18.4.2)		 2021/2022 n/a
Average duration of studies of students under mixed time status
Average duration of studies for students under mixed time status who defended a thesis (in days) (IPD18.4.3)		 2021/2022 2,499
Success rate. Percentage of students who defended their theses without asking for an extension
Ratio between the number of doctoral students who defended their theses without asking for an extension and the total number of defended thesis linked to the programme (IPD18.5.1)		 2021/2022 0
Success rate. Percentage of students who defended their theses after asking for the first extension
Ratio between the number of doctoral students who defended their theses after asking for the first extension and the total number of defended thesis linked to the programme (IPD18.5.2)		 2021/2022 0
Success rate. Percentage of students who defended their theses after asking for the second extension
Ratio between the number of doctoral students who defended their theses after asking for the second extension and the total number of defended thesis linked to the programme (IPD18.5.3)		 2021/2022 100
Percentage of "cum laude" theses
Ratio between the number of defended theses linked to the programme with "Cum Laude" qualification and the total number of defended thesis linked to the programme (IPD18.6)		 2021/2022 100
Percentage of theses with International Component
Ratio between the number of defended theses linked to the programme with International Component and the total number of defended thesis linked to the programme (IPD18.7)		 2021/2022 0
Dropout rate
Ratio between the number of doctoral students who cause permanent withdrawal from the X course and the total number of doctoral students who could re-enroll in this programme. (IPDx21)		 2021/2022 5.56
Period Value
Places offered
Number of places for new students entering PhD (IPD01)		 2020/2021 4
Demand
Number of applicants for PhD admission (IPD02)		 2020/2021 4
First-time enrollment
Number of first-time enrollment students in PhD (IPD03)		 2020/2021 1
First-time enrollment by adaptation
Number of first-time enrollment students in the program or students coming from other studies in extinction (IPD03.1)		 2020/2021 0
Total enrollment
Total number of students enrolled (IPD04)		 2020/2021 23
First-time enrollment coming from other universities
Ratio between the number of first-time enrolled students coming from other universities and the total number of first-time enrolled students in the program (IPD05)		 2020/2021 0
Percentage of foreign students
Ratio between the number of foreign students enrolled and the total number of students enrolled in the programme (IPD06)		 2020/2021 21.74
Percentage of first-time enrolled students who need training complements
Ratio between the number of students enrolled who need training complements and the total number of new students enrolled in the programme (IPD07)		 2020/2021 0
Percentage of full-time enrollees
Ratio between the number of students under full time status and the number of students enrolled in the programme (IPD08.1)		 2020/2021 60.87
Percentage of partial-time enrollees
Ratio between the number of students under half time status and the number of students enrolled in the programme (IPD08.2)		 2020/2021 4.35
Percentage of enrollees under mixed status
Ratio between the number of students under mixed status and the number of students enrolled in the programme (IPD08.3)		 2020/2021 34.78
Percentage of enrollees who carried out a stay passed by the CAPD (Outgoing)
Ratio between the number of students who carried out a stay as visiting researchers passed by the CAPD (outgoing students) and the total number of students enrolled in the programme (IPD09.1)		 2020/2021 13.04
Percentage of enrollees who carried out a stay passed by the CAPD at UDC (Incoming)
Number of students who carried out a stay as visiting researchers passed by the CAPD (incoming students) (IPD09.2)		 2020/2021 n/a
Percentage of enrollees with a grant or pre-doctoral contract
Ratio between the number of students with a grant or pre-doctoral contract and the number of students enrolled in the programme (IPD11)		 2020/2021 0
Percentage of theses defended by students who had several directors
Ratio between the number of theses defended by students of the programme who had several directors and the total number of defended theses in the programme (IPD14)		 2020/2021 100
Percentage of examination board members coming from an foreign institution
Ratio between the number of examination board members of thesis linked to the programme coming from an foreign institution and the total umber of examination board members of thesis linked to the programme (IPD17)		 2020/2021 25
Total number of defended thesis
Total number of defended thesis linked to the programme (IPD18.1)		 2020/2021 4
Percentage of defended thesis written by full-time students
Ratio between the total number of defended thesis written by students under full time status and the total number of defended theses in the programme (IPD18.2.1)		 2020/2021 50
Percentage of defended thesis written by partial-time students
Ratio between the total number of defended thesis written by students under partial time status and the total number of defended theses in the programme (IPD18.2.2)		 2020/2021 0
Percentage of defended thesis written by students under mixed status
Ratio between the total number of defended thesis written by students under mixed status and the total number of defended theses in the programme (IPD18.2.3)		 2020/2021 50
Total number of tesis written in Galician
Total number of defended thesis linked to the programme written in Galician (IPD18.3.1)		 2020/2021 0
Total number of tesis written in Spanish
Total number of defended thesis linked to the programme written in Spanish (IPD18.3.2)		 2020/2021 2
Total number of tesis written in other languages
Total number of defended thesis linked to the programme written in other languages (IPD18.3.3)		 2020/2021 2
Average duration of studies of full-time students
Average duration of studies for students under full time status who defended a thesis (in days) (IPD18.4.1)		 2020/2021 1,096
Average duration of studies of partial-time students
Average duration of studies for students under half time status who defended a thesis (in days) (IPD18.4.2)		 2020/2021 n/a
Average duration of studies of students under mixed time status
Average duration of studies for students under mixed time status who defended a thesis (in days) (IPD18.4.3)		 2020/2021 2,229
Success rate. Percentage of students who defended their theses without asking for an extension
Ratio between the number of doctoral students who defended their theses without asking for an extension and the total number of defended thesis linked to the programme (IPD18.5.1)		 2020/2021 50
Success rate. Percentage of students who defended their theses after asking for the first extension
Ratio between the number of doctoral students who defended their theses after asking for the first extension and the total number of defended thesis linked to the programme (IPD18.5.2)		 2020/2021 0
Success rate. Percentage of students who defended their theses after asking for the second extension
Ratio between the number of doctoral students who defended their theses after asking for the second extension and the total number of defended thesis linked to the programme (IPD18.5.3)		 2020/2021 50
Percentage of "cum laude" theses
Ratio between the number of defended theses linked to the programme with "Cum Laude" qualification and the total number of defended thesis linked to the programme (IPD18.6)		 2020/2021 75
Percentage of theses with International Component
Ratio between the number of defended theses linked to the programme with International Component and the total number of defended thesis linked to the programme (IPD18.7)		 2020/2021 75
Dropout rate
Ratio between the number of doctoral students who cause permanent withdrawal from the X course and the total number of doctoral students who could re-enroll in this programme. (IPDx21)		 2020/2021 10.53
Period Value
Places offered
Number of places for new students entering PhD (IPD01)		 2019/2020 4
Demand
Number of applicants for PhD admission (IPD02)		 2019/2020 8
First-time enrollment
Number of first-time enrollment students in PhD (IPD03)		 2019/2020 7
First-time enrollment by adaptation
Number of first-time enrollment students in the program or students coming from other studies in extinction (IPD03.1)		 2019/2020 0
Total enrollment
Total number of students enrolled (IPD04)		 2019/2020 24
First-time enrollment coming from other universities
Ratio between the number of first-time enrolled students coming from other universities and the total number of first-time enrolled students in the program (IPD05)		 2019/2020 14.29
Percentage of foreign students
Ratio between the number of foreign students enrolled and the total number of students enrolled in the programme (IPD06)		 2019/2020 20.83
Percentage of first-time enrolled students who need training complements
Ratio between the number of students enrolled who need training complements and the total number of new students enrolled in the programme (IPD07)		 2019/2020 0
Percentage of full-time enrollees
Ratio between the number of students under full time status and the number of students enrolled in the programme (IPD08.1)		 2019/2020 62.5
Percentage of partial-time enrollees
Ratio between the number of students under half time status and the number of students enrolled in the programme (IPD08.2)		 2019/2020 4.17
Percentage of enrollees under mixed status
Ratio between the number of students under mixed status and the number of students enrolled in the programme (IPD08.3)		 2019/2020 33.33
Percentage of enrollees who carried out a stay passed by the CAPD (Outgoing)
Ratio between the number of students who carried out a stay as visiting researchers passed by the CAPD (outgoing students) and the total number of students enrolled in the programme (IPD09.1)		 2019/2020 4.17
Percentage of enrollees who carried out a stay passed by the CAPD at UDC (Incoming)
Number of students who carried out a stay as visiting researchers passed by the CAPD (incoming students) (IPD09.2)		 2019/2020 n/a
Percentage of theses defended by students who had several directors
Ratio between the number of theses defended by students of the programme who had several directors and the total number of defended theses in the programme (IPD14)		 2019/2020 100
Percentage of examination board members coming from an foreign institution
Ratio between the number of examination board members of thesis linked to the programme coming from an foreign institution and the total umber of examination board members of thesis linked to the programme (IPD17)		 2019/2020 66.67
Total number of defended thesis
Total number of defended thesis linked to the programme (IPD18.1)		 2019/2020 1
Percentage of defended thesis written by full-time students
Ratio between the total number of defended thesis written by students under full time status and the total number of defended theses in the programme (IPD18.2.1)		 2019/2020 100
Percentage of defended thesis written by partial-time students
Ratio between the total number of defended thesis written by students under partial time status and the total number of defended theses in the programme (IPD18.2.2)		 2019/2020 0
Percentage of defended thesis written by students under mixed status
Ratio between the total number of defended thesis written by students under mixed status and the total number of defended theses in the programme (IPD18.2.3)		 2019/2020 0
Total number of tesis written in Galician
Total number of defended thesis linked to the programme written in Galician (IPD18.3.1)		 2019/2020 0
Total number of tesis written in Spanish
Total number of defended thesis linked to the programme written in Spanish (IPD18.3.2)		 2019/2020 0
Total number of tesis written in other languages
Total number of defended thesis linked to the programme written in other languages (IPD18.3.3)		 2019/2020 1
Average duration of studies of full-time students
Average duration of studies for students under full time status who defended a thesis (in days) (IPD18.4.1)		 2019/2020 1,518
Average duration of studies of partial-time students
Average duration of studies for students under half time status who defended a thesis (in days) (IPD18.4.2)		 2019/2020 n/a
Average duration of studies of students under mixed time status
Average duration of studies for students under mixed time status who defended a thesis (in days) (IPD18.4.3)		 2019/2020 n/a
Success rate. Percentage of students who defended their theses without asking for an extension
Ratio between the number of doctoral students who defended their theses without asking for an extension and the total number of defended thesis linked to the programme (IPD18.5.1)		 2019/2020 0
Success rate. Percentage of students who defended their theses after asking for the first extension
Ratio between the number of doctoral students who defended their theses after asking for the first extension and the total number of defended thesis linked to the programme (IPD18.5.2)		 2019/2020 100
Success rate. Percentage of students who defended their theses after asking for the second extension
Ratio between the number of doctoral students who defended their theses after asking for the second extension and the total number of defended thesis linked to the programme (IPD18.5.3)		 2019/2020 0
Percentage of "cum laude" theses
Ratio between the number of defended theses linked to the programme with "Cum Laude" qualification and the total number of defended thesis linked to the programme (IPD18.6)		 2019/2020 100
Percentage of theses with International Component
Ratio between the number of defended theses linked to the programme with International Component and the total number of defended thesis linked to the programme (IPD18.7)		 2019/2020 100
Dropout rate
Ratio between the number of doctoral students who cause permanent withdrawal from the X course and the total number of doctoral students who could re-enroll in this programme. (IPDx21)		 2019/2020 0

theses

publications

This is a sample of the scientific production of the PhD students and is intended to guide prospective students interested in this program. Under no circumstances should it be considered a full and exhaustive list of all the scientific production of the students. The information is supplied by the PhD students themselves in a relatively unstructured manner but it has been checked and approved by the academic committee.

Artículos en revistas internacionales
Naveira-Pazos C, Veiga MC, Kennes C. Accumulation of lipids by the oleaginous yeast Yarrowia lipolytica grown on carboxylic acids simulating syngas and carbon dioxide fermentation. Bioresour Technol. 2022;360:127649. doi:10.1016/J.BIORTECH.2022.127649
Saavedra-Bouza, A., Escuder‑Rodríguez, J.-J., deCastro, M.-E., Becerra, M., & González-Siso, M.-I. (2023). Xylanases from thermophilic archaea: A hidden treasure. Current Research in Biotechnology5, 100116. https://doi.org/10.1016/j.crbiot.2022.11.003
Ruiz-Romero C, Fernández-Puente P, González L, Illiano A, Lourido L, Paz R, Quaranta P, Perez-Pampín E, González A, Blanco FJ, Calamia V. Association of the serological status of rheumatoid arthritis patients with two circulating protein biomarkers: A useful tool for precision medicine strategies. Front Med (Lausanne). 2022 Oct 28;9:963540. doi: 10.3389/fmed.2022.963540. PMID: 36388911; PMCID: PMC9651940.
Junquera López-Seijas, Diego Miranda-Balbuena, Alba Iglesias-Fente, Marta Sacristán-Santos, Natalia Carballo-Pedrares, María C. Arufe, Ana Rey-Rico, Juan Fafián-Labora, Development of new non-viral systems for genetic modification of senescent cells,Molecular Therapy - Nucleic Acids, Volume 32, 2023, Pages 302-317, ISSN 2162-2531, https://doi.org/10.1016/j.omtn.2023.03.010. (https://www.sciencedirect.com/science/article/pii/S2162253123000690) Abstract: Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, gene therapy has emerged as a powerful tool for treating age-associated diseases by the transference of specific genes into the target cell population. However, the high sensitivity of senescent cells significantly precludes their genetic modification via classical viral and non-viral systems. Niosomes are self-assembled non-viral nanocarriers that exhibit important advantages due to their elevated cytocompatibility, versatility, and cost-efficiency, arising as a new alternative for genetic modification of senescent cells. In this work, we explore for the first time the use of niosomes for genetic modification of senescent umbilical cord-derived mesenchymal stem cells. We report that niosome composition greatly affected transfection efficiency; those formulations prepared in medium with sucrose and containing cholesterol as helper lipid being the most suitable to transfect senescent cells. Moreover, resulting niosome formulations exhibited a superior transfection efficiency with a markedly less cytotoxicity than the commercial reagent Lipofectamine. These findings highlight the potentiality of niosomes as effective vectors for genetic modification of senescent cells, providing new tools for the prevention and/or treatment of age-related diseases. Keywords: MT: Delivery Strategies; senescence; aging; umbilical cord mesenchymal stem cells; gene therapy; non-viral vectors; niosomes
Mycena pseudoseta (Agaricales, Mycenaceae), primer registro en Europa Pendente publicacion finales do 2023 no boletín da Sociedad Micológica de Madrid
Natalia Carballo-Pedrares, Federica Ponti, Junquera Lopez-Seijas, Diego Miranda-Balbuena, Nina Bono, Gabriele Candiani, Ana Rey-Rico, Non-viral gene delivery to human mesenchymal stem cells: a practical guide towards cell engineering,Journal of Biological Engineering, Volume 17, 2023, DOI: 10.1186/s13036-023-00363-7 (https://jbioleng.biomedcentral.com/articles/10.1186/s13036-023-00363-7) Abstract: In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the field of cell therapy for treating cartilage and bone injuries. Despite the tri-lineage multipotency, proliferative properties, and potent immunomodulatory effects of hMSCs, their clinical potential is hindered by donor variations, limiting their use in medical settings. To address this challenge, gene delivery technologies have emerged as a promising approach to modulate the phenotype and commitment of hMSCs towards specific cell lineages, thereby enhancing osteochondral repair strategies. This review provides a comprehensive overview of current non-viral gene delivery approaches used to engineer MSCs, highlighting key factors such as the choice of nucleic acid or delivery vector, transfection strategies, and experimental parameters. Additionally, it outlines various protocols and methods for qualitative and quantitative evaluation of their therapeutic potential as a delivery system in osteochondral regenerative applications. In summary, this technical review offers a practical guide for optimizing non-viral systems in osteochondral regenerative approaches.
Robles-Iglesias R, Naveira-Pazos C, Fernández-Blanco C, Veiga MC, Kennes C. Factors affecting the optimisation and scale-up of lipid accumulation in oleaginous yeasts for sustainable biofuels production. Renew Sustain Energy Rev 2023;171:113043. https://doi.org/10.1016/j.rser.2022.113043.
Robles-Iglesias, R., Naveira-Pazos, C., Fernández-Blanco, C., Veiga, M. C., & Kennes, C. (2023). Factors affecting the optimisation and scale-up of lipid accumulation in oleaginous yeasts for sustainable biofuels production. Renew. Sustain. Energy Rev.171:, 113043. https://doi.org/10.1016/j.rser.2022.113043
Fernández-Blanco, C., Robles-Iglesias, R., Naveira-Pazos, C., Veiga, M. C., & Kennes, C. (2023). Production of biofuels from C1-gases with Clostridium and related bacteria—Recent advances. Microb. Biotechnol.16:, 726–741. https://doi.org/10.1111/1751-7915.14220
Fernández-Blanco, C., Veiga, M. C., & Kennes, C. (2022). Efficient production of n-caproate from syngas by a co-culture of Clostridium aceticum andClostridium kluyveriJ. Environ. Manage.302:, 113992. https://doi.org/10.1016/j.jenvman.2021.113992
Fernández‐Blanco, C., Robles‐Iglesias, R., Naveira‐ Pazos, C., Veiga, M. C., & Kennes, C. (2023). Production of biofuels from C1‐gases with Clostridium and related bacteria— Recent advances. Microbial Biotechnology16(4), 726- 741.
Robles-Iglesias, R., Naveira-Pazos, C., Fernández-Blanco, C., Veiga, M. C., & Kennes, C. (2023). Factors affecting the optimisation and scale-up of lipid accumulation in oleaginous yeasts for sustainable biofuels production. Renewable and Sustainable Energy Reviews171, 113043. 
Natalia Carballo-Pedrares, Junquera López-Seijas, Diego Miranda-Balbuena, Ibán Lamas, Julián Yáñez, Ana Rey-Rico, Gene-activated hyaluronic acid-based cryogels for cartilage tissue engineering, Journal of Controlled Release, Volume 362, 2023, Pages 606-619, ISSN 0168-3659, https://doi.org/10.1016/j.jconrel.2023.09.008. https://www.sciencedirect.com/science/article/pii/S016836592300593X Abstract: Articular cartilage injuries are very frequent lesions that if left untreated may degenerate into osteoarthritis. Gene transfer to mesenchymal stem cells (MSCs) provides a powerful approach to treat these lesions by promoting their chondrogenic differentiation into the appropriate cartilage phenotype. Non-viral vectors constitute the safest gene transfer tools, as they avoid important concerns of viral systems including immunogenicity and insertional mutagenesis. However, non-viral gene transfer usually led to lower transfection efficiencies when compared with their viral counterparts. Biomaterial-guided gene delivery has emerged as a promising alternative to increase non-viral gene transfer efficiency by achieving sustained delivery of the candidate gene into cellular microenvironment. In the present study, we designed hyaluronic acid-based gene-activated cryogels (HACGs) encapsulating a novel formulation of non-viral vectors based on niosomes (P80PX) to promote MSCs in situ transfection. The developed HACG P80PX systems showed suitable physicochemical properties to promote MSCs in situ transfection with very low cytotoxicity. Incorporation of a plasmid encoding for the transcription factor SOX9 (psox9) into HACG P80PX systems led to an effective MSCs chondrogenic differentiation with reduced expression of fibrocartilage and hypertrophic markers. The capacity of the developed systems to restore cartilage extracellular matrix was further confirmed in an ex vivo model of chondral defect. Keywords: Cartilage repair; Gene therapy; Non-viral vectors; Niosomes; P80PX; Gene activated cryogel; HACG; Mesenchymal stem cells
Capítulo de Libro
José Díaz, Raquel Núñez-Fernández, & Veloso, J. (2023). Padrón Peppers, Some Are Hot, and Some Are Not. In Orlex Baylen Yllano (Ed.), Capsicum (pp. Ch. 2). IntechOpen. 10.5772/intechopen.110435
Kennes-Veiga, D.Fernández-Blanco, C.Veiga, M.Kennes, C.2023Ethanol production from syngas (chapter 6). In: M.R. RahimpourM.A. MakaremM. Meshksar (Eds.) Advances in synthesis gas: methods, technologies and applications, Vol. 3: syngas products and usages: chemicals production from syngasAmsterdam, The Netherlands: Elsevier, pp. 147171
Kennes-Veiga David M., Villanueva-Perales Ángel L., Haro Pedro, Naveira-Pazos Cecilia, Veiga María C., Kennes Christian. (s. f.). Syngas conversion to biofuels: Recent progress. En Advances in Biofuels Production, Optimization and Applications. Elsevier.
Otras publicaciones
New Thermophilic Protein with Xylanase Activity
Artículos en revistas internacionales
Escuder-Rodríguez, J.-J., Decastro, M.-E., Saavedra-Bouza, A., González-Siso, M.-I., and Becerra, M. (2022). Bioprospecting for Thermozymes and Characterization of a Novel Lipolytic Thermozyme Belonging to the SGNH / GDSL Family of Hydrolases. Int. J. Mol. Sci. 23, 5733.
Arslan, K., Schoch, T., Höfele, F., Herrschaft, S., Oberlies, C., Bengelsdorf, F., Veiga, M. C., Dürre, P., & Kennes, C. (2022). Engineering Acetobacterium woodii for the production of isopropanol and acetone from carbon dioxide and hydrogen. Biotechnology Journal, September 2021, 1–12. https://doi.org/10.1002/biot.202100515
Escuder-Rodríguez, J.-J., González-Suarez, M., Decastro, M.-E., Saavedra-Bouza, A., González-Siso, M.-I., & Becerra, M. (2022). Characterization of a novel thermophilic metagenomic GH5 endoglucanase heterologously expressed in Escherichia coli and Saccharomyces cerevisiae. Biotechnology for Biofuels and Bioproducts15(76), 1–13. https://doi.org/10.1186/s13068-022-02172-4
Mycena morenoi VILLARREAL M.1, TRABA J.M.2, COUCEIRO A.3,NAVEIRA H.4, & VILA-SANJURJO A. pendiente publicacion en Fungal Planet 2022-2023
Tres especies nuevas de Mycena sección Amparoina de la Península IbéricaTRABA J.M.2, COUCEIRO A.3,VILLARREAL M.1, NAVEIRA H.4, & VILA-SANJURJO A.5 Pendiente publicacion en revista internacional 
Artículos en revistas nacionales
Russula intermedia P-Karst primer hallazgo bajo Corylus avellana MONEDERO L.C.1, TRABA J.M.2,NAVEIRA H. 3, & VILA-SANJURJO A.4 Entregado y Pendiente de publicación en el Boletín de la Sociedad extremeña de Micología octubre 2022
Mycena fragosa Mycenaceae), a new species from the fragas in northwestern Spain VILLARREAL M.1, TRABA J.M.2, COUCEIRO A.3,NAVEIRA H.4, & VILA-SANJURJO A.5   Entregado y pendiente de publicación en la revista de la Sociedad Ibérica de Micología noviembre 2022
Artículos en revistas internacionales
Calero, R., Iglesias-Iglesias, R., Kennes, C., Veiga, M.C., 2018. Organic loading rate effect on the acidogenesis of cheese whey: a comparison between UASB and SBR reactors. Environ. Technol. (United Kingdom) 39, 3046–3054. https://doi.org/10.1080/09593330.2017.1371796
Iglesias-Iglesias, R., Campanaro, S., Treu, L., Kennes, C., Veiga, M.C., 2019. Valorization of sewage sludge for volatile fatty acids production and role of microbiome on acidogenic fermentation. Bioresour.Technol. 291, 121817. https://doi.org/10.1016/j.biortech.2019.121817
Iglesias-Iglesias, R., Fernandez-Feal, M.M. del C., Kennes, C., Veiga, M.C., 2020. Valorization of agro-industrial wastes to produce volatile fatty acids: combined effect of substrate/inoculum ratio and initial alkalinity. Environ. Technol. 0, 1–33. https://doi.org/10.1080/09593330.2020.1743370
Iglesias-Iglesias, R., Kennes, C., Veiga, M.C., 2020. Valorisation of sewage sludge in co-digestion with cheese whey to produce volatile fatty acids. Waste Manag. 118, 541–551.https://doi.org/10.1016/j.wasman.2020.09.002
Lagoa-Costa, B., Kennes, C., Veiga, M.C., 2020. Cheese whey fermentation into volatile fatty acids in an anaerobic sequencing batch reactor. Bioresour. Technol. 308, 123226.
Lourido L, Balboa-Barreiro V, Ruiz-Romero C, Rego-Pérez I, Camacho-Encina M, Paz-González R, Calamia V, Oreiro N, Nilsson P, Blanco FJ. A clinical model including protein biomarkers predicts radiographic knee osteoarthritis: a prospective study using data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2021 Aug;29(8):1147-1154. doi: 10.1016/j.joca.2021.04.011. Epub 2021 Apr 30. PMID: 33933586.
Pacheco Compaña Francisco Javier, Rodríguez Pérez Esther, Bugallo Sanz Juan Ignacio, Fernández Quinto Alejandro, González Rodriguez Alba. Factores relacionados con el riesgo de reintervención en pacientes operados de reducción cerrada de fractura de huesos propios. Cir. plást. iberolatinoam.  [Internet]. 2021  Mar [citado  2021  Ago  19] ;  47( 1 ): 81-86. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0376-78922021000100011&lng=es.  Epub 02-Ago-2021.  https://dx.doi.org/10.4321/s0376-78922021000100011.
Robles-Iglesias, R., Veiga, M. C., & Kennes, C. (2021). Carbon dioxide bioconversion into single cell oils (lipids) in two reactors inoculated with Acetobacterium woodii and Rhodosporidium toruloides. Journal of CO2 Utilization52, 101668.
Young-Kyoung Park, Cristina González-Fernández, Raúl Robles-Iglesias, Lea Vidal, Pierre Fontanille, Christian Kennes, Elia Tomás Pejó, Jean-Marc Nicaud, Patrick Fickers, Bioproducts generation from carboxylate platforms by the non-conventional yeast Yarrowia lipolyticaFEMS Yeast Research, 2021;, foab047, https://doi.org/10.1093/femsyr/foab047
Arslan K, Veiga MC, Kennes C. Autotrophic (C1-gas) versus heterotrophic (fructose) accumulation of acetic acid and ethanol in Clostridium aceticum. Bioresour Technol. 2021 Oct;337:125485.
Sonia Pereira-Crespo, A. Botana, M. Veiga, L. González, C. Resch, V. García-Souto, R. Lorenzana, N. Núñez-Sánchez, G. Flores-Calvete. Autenticação da origem alimentar  do leite de vaca por meio de NIRS. Pastagens e Forragens, Volumen 39/40 , 2020, páginas 49-57. ISSN 0870-6263
Artículos en revistas nacionales
A. Botana, s. Pereira-Crespo, M. Veiga, L. Gonzalez, V. Garcia-Souto, C. Resch, R. Lorenzana, G. Flores-Calvete. Sistemas de producción, calidad y composición de la leche de vaca en Galicia. Vaca Pinta, Volumen 21, Diciembre 2020, Páginas 110-121; ISBN: 978-84-09-265541-1
J. Valladares, M. Veiga, V. Souto, S.Pereira, G. Flores. Influencia del riego en el maíz forrajero. Resultados preliminares de dos ensayos en el interior de Galicia. Vaca Pinta, Volumen 23, Marzo 2021, Páginas 153-161; ISBN: 978-84-09-29159-5
M.D. Báez Bernal, M.I. García Pomar, J.F. Castro Insua, A. Louro López , C. Gilsanz Rey, V. García Souto, C. Santiago Andión. Rotación do millo con cultivos de inverno: producións dos cultivos independentes e efectos da rotación, Vaca Pinta, Volumen 23, Marzo 2021, Páginas 140-153, ISBN:978-84-09-29159-5
Capítulo de Libro
Lourido L, Paz-González R, Ruiz-Romero C, Nilsson P, Blanco FJ. Serum Proteomic Profiling in Rheumatoid Arthritis by Antibody Suspension Bead Arrays. Methods Mol Biol. 2021;2259:143-151. doi: 10.1007/978-1-0716-1178-4_8. PMID: 33687712.
CIRUGÍA ONCOLÓGICA DE LA MAMA. TÉCNICAS ONCOPLASTICAS Y  RECONSTRUCTIVAS. 4º EDICIÓN, ELSEVIER40. SARCOMAS DE MAMA Y PARED TORÁCICA: ALTERNATIVAS QUIRÚRGICASISBN: 978-84-9113-112-0Depósito legal: B. 26.336-2018
Artículos en revistas internacionales
Analysis of endogenous peptides released from osteoarthritic cartilage unravels novel pathogenic markers.Mol Cell Proteomics (2019)DOI:10.1074/mcp.RA119.001554
Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis.Therapeutic Advances in Chronic Disease (2019)https://doi.org/10.1177/2040622319870013
Influence of preparation procedures on the phenolic content, antioxidant and antidiabetic activities of green and black teas.Brazilian Journal of Pharmaceutical Sciences (2019)http://dx.doi.org/10.1590/s2175-97902019000117695
López-Senra; Estefanía, Casal-Beiroa, Paula; López-Álvarez, Miriam; Serra, Julia; González, Pío; Valcárcel, Jesús; Vázquez, José Antonio; Fernández-Burguera, Elena; Blanco, Francisco J.; Magalhaes, Joana (2020)"Impact of prevalence ratios of chondroitin sulphate (CS)-4 and 6- isomers derived from marine sources in cell proliferation and chondrogenic differenciation processes" J Mar Drugs 2020
Casal-Beiroa, P. González, P., Blanco, FJ., Magalhães, J. (2020) Molecular analysis of the destruction of articular joint tissues by Raman spectroscopy. Expert Review of Molecular DiagnosticsDOI: 10.1080/14737159.2020.1782747
Martínez Diz, M.P., Andrés-Sodupe, M., Berbegal, M., Bujanda, R., Díaz-Losada, E., Gramaje, D. 2020. Droplet Digital PCR Technology for Detection of Ilyonectria liriodendri from Grapevine Environmental Samples. Plant Dis. 104: 1144-1150. https://doi.org/10.1094/PDIS-03-19-0529-RE
Maldonado-González, M.M., Martínez-DizM.P.Andrés-Sodupe, M., Bujanda, R., Díaz-Losada, E., Gramaje, D. 2020. Quantification of Cadophora luteo-olivacea from grapevine nursery stock and vineyard soil using droplet digital PCR. Plant Dis. https://doi.org/10.1094/PDIS-09-19-2035-RE
Martínez-Diz, M.P., Eichmeier, A., Spetik, M., Bujanda, R., Díaz-Fernández, A., Díaz-Losada, E., Gramaje, D. 2020. Grapevine pruning time affects natural wound colonization by wood-invading fungi. Fungal Ecol. (accepted with minor revision). BioRxiv doi: https://doi.org/10.1101/2020.04.20.050955
Martínez-Diz, M.P., Díaz-Losada, E., Andrés-Sodupe, M., Bujanda, R., Maldonado-González, M.M., Ojeda, S., Yacoub, A., Rey, P., Gramaje, D. 2020. Field evaluation of biocontrol agents against black-foot and Petri diseases of grapevine. Submitted to Pest Manag. Sci. (under revision). BioRxiv doi: https://doi.org/10.1101/2020.05.19.101568
Martínez-Diz, M.P., Díaz-Losada, E., Díaz-Fernández, A., Bouzas-Cid, A., Gramaje, D. 2020. Protection of grapevine pruning wounds against Phaeomoniella chlamydospora and Diplodia seriata by biological and chemical methods. Submitted to Crop Prot. (under revision). BioRxiv doi: https://doi.org/10.1101/2020.05.26.117374
Gramaje, D., Berlanas, C., Martínez-Diz, M.P., Díaz-Losada, E., Antonielli, L., Gorfer, M., Compant, S. 2020. Comparative genomic of Dactylonectria torresensis strains from grapevine, soil and weed highlights potential mechanisms in pathogenicity and endophytic lifestyle. Submitted to IMA Fungus (under revision).
Analysis of endogenous peptides released from osteoarthritic cartilage unravels novel pathogenic markers Patricia Fernández-Puente1*, Lucía González-Rodríguez1*, Valentina Calamia1, Flor Picchi1, Lucía Lourido1, María Camacho-Encina1, Natividad Oreiro1, Beatriz Rocha1, Rocío Paz1, Anabel Marina2, Carlos García2, Francisco J Blanco1,3# and Cristina Ruiz- RomeroMol Cell Proteomics Papers in Press. Published on July 27, 2019 as Manuscript RA119.001554
Gonzaga González,  S.  E., Fernández  Romay,  Y.,  Bernal  Pita  Da  Veiga,  M.  Á., & Moreno Herrera, A.  (2019).  Fitorremediación de aguas residuales porcícolas mediante el uso de semillas Moringa oleifera LAM. Revista CientíficaAgroecosistemas, 7(2), 132-139. Recuperado de https://aes.ucf.edu.cu/index.php/aes/article/view/285/308
Ordoñez Castillo, F. M., Bernal Pita Da Veiga, M. A., Vidal Gonzalez N. P., & Moreno Herrera, A. (2019). Efectos antioxidantes de Moringa oleifera LAM en vitroplantas de banano clon Williams enraizadas en sistemas de inmersión temporal RITA. Revista Científica Agroecosistemas, 7(3), 57-63. Recuperado de file:///C:/Users/Usuario/Downloads/document%20(5).pdf
García Batista, R. M., Castillo Ontaneda, A. L., & Moreno Herrera, A. (2020). Características y uso del sistema de inmersión temporal en la propagación in vitro en la familia bromeliaceae. Revista Científica Agroecosistemas, 8(1), 64-67. Recuperado de file:///C:/Users/Usuario/Downloads/document%20(6).pdf
Castillo Ontaneda, A. L., Moreno Herrera, A., García Batista, R. M. (2020). Eficiencia del sistema de inmersión temporal frente al método de propagación convencional in vitro. Revista Metropolitana de Ciencias Aplicadas, 3(2), 173182. Recuperado de https://remca.umet.edu.ec/index.php/REMCA/article/view/284/315
Gonzalez Porto SA, Cano Leira MA, Gonzalez Rodríguez A, Alvarez Jorge A, Capitolunate arthrodesis versus four-corner arthrodeses in scaphoid nonunionadvanced collapsed wrist. Rev Iberam Cir Mano, 2019;47:32-38
Carlos A. García-González & Cristina Silvar. (2020). Plants Phytochemical Assessment of Native Ecuadorian Peppers (Capsicum spp.) and Correlation Analysis to Fruit Phenomics. Plants 2020, 9, 986. https://doi.org/10.3390/plants9080986https://www.mdpi.com/2223-7747/9/8/986#cite
Arslan, K., Bayar, B., Abubackar, H. N., Veiga, M. C., & Kennes, C. (2019). Solventogenesis in Clostridium aceticum producing high concentrations of ethanol from syngas. Bioresource technology292, 121941.
Artículos en revistas nacionales
Martínez-Díz, M.P., Díaz-Losada, E., Gramaje. D. 2020. Manejo integrado de las enfermedades de la madera en viveros de vid. Agricultura 1035: 36-40.
Martínez-Diz, M.P., Díaz-Losada, E., Díaz-Fernández, A., Bouzas-Cid, Y., Bartolomé-Lozano, J.L., Gramaje, D. 2020. Evaluación de productos para la protección de heridas de poda contra hongos de la madera de la vid. Vida Rural junio 2020: 50-56.
González Porto SA, Silva Díaz MT, Reguera Arias A, Pombo Otero J, González Rodríguez A, Valero Gasalla J, et al. A Comparative Study of Doppler Ultrasound against Temporary Artery Biopsy in the Diagnosis of Giant Cell Arteritis. Reumatol Clin. 2018 Oct 11
Capítulo de Libro
Casal-Beiroa, P.; Blanco, F.J.; Magalhães, J. (2020) Raman spectroscopy for cartilage damage severity, degradation and repair assessment. En González, P. (Ed.) Avances en la Bioingeniería para el envejecimiento saludable, pp 43-54 Universidade de Vigo, Vigo, España
Libro
Gramaje, D., Armengol, J., Berbegal, M., Chacón, J.L., Barajas, E., Rubio Cano, J.A., Muñoz, R.M., Martínez-Diz, M.P., Díaz-Losada, E. 2020. Guía sobre las enfermedades fúngicas de la madera de la vid. Ministerio de Agricultura, Pesca y Alimentación, Gobierno de España. En prensa.
Otras publicaciones
Martínez-Diz, M.P., Andrés-Sodupe, M., Bujanda, R., Díaz-Losada, E., Maldonado-González, M.M., Ojeda, S., Gramaje, D. 2020. Evaluación de agentes de control biológico (ACB) contra el Pie negro y la enfermedad de Petri en condiciones de campo. Ministerio de Agricultura, Pesca y Alimentación, Gobierno de España. En prensa.
Andrés-Sodupe, M., Martínez-Diz, M.P., Bujanda, R., Maldonado-González, M.M., Díaz-Fernández, A., Díaz-Losada, E., Ojeda, S., Gramaje, D. 2020. Evaluación de infecciones naturales por hongos de la madera en viñedos de La Rioja, Navarra y Galicia. Ministerio de Agricultura, pesca y alimentación, Gobierno de España. En prensa.
Artículos en revistas internacionales
Martínez-DizM.P., Eichmeier, A.,Andrés-Sodupe, M., Bujanda, R., Díaz-Losada, E., Gramaje, D. 2019. Soil-plant compartments affect fungal microbiome diversity and composition in grapevine. Fungal Ecology 41: 234-244. https://doi.org/10.1016/j.funeco.2019.07.003 
Berlanas, C., Ojeda, S., López-Manzanares, B., Andrés-Sodupe, M., Bujanda, R., Martínez-Diz, M.P., Díaz-Losada, E., Gramaje, D. 2019. Occurrence and diversity of black-foot disease fungi in symptomless grapevine nursery stock in Spain. Plant Disease. DOI: 10.1094/PDIS-03-19-0484-RE 
Martínez-Diz, M.P., Díaz-Losada, E., Barajas, E., Ruano-Rosa, D., Andrés-Sodupe, M, Gramaje, D. 2019. Screening of Spanish Vitis viniferagermplasm for resistance to Phaeomoniella chlamydospora. Scientia Horticulturae, 246: 104–109. https://doi.org/10.1016/j.scienta.2018.10.049
Martínez-Diz, M.P., Díaz-Losada, E., Armengol, J., León, M., Berlanas, C., Andrés-Sodupe, M. y Gramaje, D. 2018.First report of Ilyonectria robusta causing black foot disease of grapevine in Spain. Plant Disease 102:2381. https://doi.org/10.1094/PDIS-05-18-0730-PDN
Gálvez Ramírez, M. I., Moreno Herrera, A., & Fernández Romay, Y. (2019). Efecto biorremediador de semillas de Moringa Oleífera Lam (Mol) para mejorar la calidad del agua de consumo en granjas avícolas. Revista Científica Agroeco- sistemas, 7(1), 125-133. Recuperado de https://aes.ucf.edu.cu/index.php/aes
Artículos en revistas nacionales
Martínez-Díz, M.P., Díaz-Losada, E., Berbegal, M., Andrés-Sodupe, M., Gramaje. D. 2019. Variaciones espaciales en las comunidades fúngicas en suelos de viñedos y su interacción con la enfermedad del pie negro.Phytoma España 311:1-7 (Libro).
Maldonado, M.M., Andrés Sodupe, M., Berlanas, C., Bujanda, R. and Gramaje, D., Martínez Diz, M.P.y Díaz Losada, E. 2018. Enfermedades fúngicas de la madera de la vid: líneas de investigación actuales y últimos avances para su control. Cuaderno de Campo nº 61 - Junio 2018: 28-35. 
Notas
Gálvez Ramírez, M. I., Moreno Herrera, A., & Fernández Romay, Y. (2019). Efecto biorremediador de semillas de Moringa Oleífera Lam (Mol) para mejorar la calidad del agua de consumo en granjas avícolas. Revista Científica Agroecosistemas, 7(1), 125-133. Recuperado de https://aes.ucf.edu.cu/index.php/aes
Otras publicaciones
Martínez-Diz, M.P., Andrés-Sodupe, M., Bujanda, R., Díaz-Losada, E., Maldonado-González, M.M, Ojeda, S., Rey, P., Yacoub, A., Gramaje, D. 2019. Screening of biocontrol agents against black-foot and Petri diseases under field conditions. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Martínez-Diz, M.P., Eichmeier, A., Andrés-Sodupe, M., Bujanda, R., Díaz-Fernández, A., Díaz-Losada, E., Maldonado-González, M.M, Ojeda, S., Gramaje, D. 2019. Natural infections of pruning wounds by fungal trunk pathogens in mature vineyards in Galicia (northwest Spain). Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Berlanas, C., Armengol, J., Berbegal, M., Berraf, A., Carlucci, A., Eichmeier, A., Halleen, F., Martínez-Diz, M.P., Mostert, L., Reis, P., Gramaje, D. 2019. Genetic analysis of Dactylonectria torresensis populations from grapevine using microsatellite markers. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Andrés-Sodupe, M., Berlanas, C., Bujanda, R., Díaz-Losada, E., López-Manzanares, B., Martínez-Diz, M.P., Ojeda, S., Gramaje, D. 2019. Characterization and pathogenicity of black-foot disease pathogens isolated from symptomless grapevine nursery stock in Spain. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Maldonado-González, M.M., Andrés-Sodupe, M., Berbegal, M., Bujanda, R., Díaz-Losada, E, Martínez-DizM.P., Gramaje, D. 2019. Droplet digital PCR technology for detection and quantification of black-foot disease pathogens and Cadophora luteo-olivacea from grapevine nursery stock and vineyard soil. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Martínez-DizM.P., Andrés-Sodupe, M., Bujanda, R., Díaz-Losada, E., Gramaje, D. 2019. Grapevine belowground compartments affect fungal trunk pathogens composition. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Gramaje, D., Berlanas, C., Díaz-Losada, E., Martínez-Diz, M.P., Antonielli, L., Gorfer, M., Compant, S. 2019. Comparative genomics of Dactylonectria torresensis strains from grapevine, soil and weeds highlight potential mecanisms in pathogenicity and lifestyle. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD).
Martínez-Diz, M.P., Ayres, M., Sosnowski, M. 2019. Grapevine cultivar variability in colonization by Phaeomoniella chlamydospora and Phaeoacremonium minimum. Libro de resúmenes del congreso. 11th International Workshop on Grapevine Trunk Diseases (IWGTD). 
Martínez-Diz, M.P., Andrés-Sodupe, M., Berbegal, M., Díaz-Losada, E., Gramaje, D. 2018. Fungal community structure form soil to grapevine root and its interaction with black-foot disease. Libro de resúmenes del congreso. International Congress on Grapevine and Wine Sciences (ICGWS). 
Martínez-Diz, M.P., Díaz-Losada, E., Barajas, E., Ruano-Rosa, D., Andrés-Sodupe, M., Gramaje, D. 2018. Phenotyping assays to identify tolerant grapevine cultivars to Phaeomoniella chlamydospora infection. Libro de resúmenes del congreso. International Congress on Grapevine and Wine Sciences (ICGWS).
González-Domínguez, E., Berlanas, C., Martínez-Diz, M.P., Díaz-Losada, E., Gramaje, D, Armengol, J., Berbegal, M. 2018. Environmental factors associated with dispersal of Phaeomoniella chlamydospora, causal agent of esca disease of grapevine. Libro de resúmenes del congreso. International Congress on Grapevine and Wine Sciences (ICGWS).
Díaz-Losada, E., Díaz-Fernández, A., Martínez-Diz M.P., Cortés-Dieguez S. 2018. Identification by GC-MS of the main free and glycosidically volatile compounds in grapes from Vitis vinifera cv. Albilla over three consecutive vintages. Libro de resúmenes del congreso. International Congress on Grapevine and Wine Sciences (ICGWS).
Martínez-Diz, M.P., Berlanas, C., Gramaje, D. y Díaz-Losada, E. Estudio preliminar: Evaluación de la tolerancia de cultivares de Vitis viniferaL. a hongos asociados a las enfermedades de la madera de la vid. 2018. Ministerio de Agricultura, pesca y alimentación, Gobierno de España. Reuniones del Grupo de Trabajo de Experimentación en Viticultura y Enología, 32ª Reunión: 97-104.
Martínez-Diz, M.P., Díaz-Losada, E., Díaz-Fernández, A. y Cortés-Diéguez, S. Perfil aromático de variedades tintas cultivadas en Galicia. 2018. Ministerio de Agricultura, pesca y alimentación, Gobierno de España. Reuniones del Grupo de Trabajo de Experimentación en Viticultura y Enología, 32ª Reunión:115-122.
Rodríguez, R., & Moreno, A. (2018). Superoxide dismutase activity and jasmonic acid during in vitro-ex vitro transition of pineapple (Ananas comosus (L.) Merr.) micropropagated plantlets. African Journal of Biotechnology17(50), 1397–1402. https://doi-org.accedys.udc.es/10.5897/ajb2018.16618
Artículos en revistas internacionales
Bermúdez, N., Kennes, C., Veiga, M.C., 2017.Anaerobic digestion of tuna waste for the production of volatile fatty acids. Waste Management. 68,96-102.
Moreno Herrera, A., García Batista, R. G., García, C., & Montes de Oca Suárez, J. L. (2017). Análisis ecosistémicosustentable de una Biofábrica de vitroplantas en predios agrícolas de la UTMACH, Ecuador.Revista CientíficaAgroecosistemas, 5(1-Ext), 140-149. Recuperado de http://aes.ucf.edu.cu/index.php/aes/index
González Porto SA, González Rodríguez A, Palacios García P, Rodríguez Pérez E, Yebra Pimentel MTExperiencia en el desbridamiento con Nexobrid y cura húmeda con Prontosan wound gel en el paciente quemado. Cir. plást iberolatinoam. 2018 Mar; 44(1):93-111
González Porto SA, Domenech N, González Rodríguez A, Avellaneda Oviedo EM, Blanco FJ, Arufe Gonda MC, et al. The addition of albumin improves Schwann cells viability in nerve cryopreservation. Cell Tissue Bank. 2018 Apr 26
Ugarte-Barco, F., Lima Morales, K. A., Bernal Pita Da Veig, M. A., & Moreno-Herrera, A. (2018). Estudios preliminares del efecto fortificante de extractos de Moringa Oleifera Lam. en vitroplantas del clon Williams en aclimatación. Revista Científica Agroecosistemas, 6(2), 47-55. Recuperado de http://aes.ucf.edu.cu/index.php/aes/index
P. Casal Beiroa, E.F. Burguera, T. Hermida Gomez, N. Goyanes, N. Oreiro Villar, F.J. Blanco, P. Gonzalez, J. Magalhaes, Optical biomarkers for the early diagnosis of osteoarthritis, Osteoarthritis and Cartilage, 26, 1, 2018, S191, https://doi.org/10.1016/j.joca.2018.02.409.
Artículos en revistas nacionales
Avellaneda Oviedo EM, González Rodríguez A, González Porto SA, Palacios Garrcía P, Rodríguez Pérez E, Bugallo Sanz JI. Injertos en heridas. Heridas y cicatrización. 2018 Jun; 8(2):6-15
García-González, C.; Álvarez-Chuncho, L.; Gutiérrez-Peralta, N.; Cabrera-Gia, C.; Yanez-Jara, F.; Ajila-Solorzano, K. (2018). DETERMINACIÓN POTENCIOMÉTRICA DE VITAMINA C EN NARANJA Y MANDARINA, 2, 54–62. Retrieved from http://investigacion.utmachala.edu.ec/proceedings/index.php/utmach/article/view/272/222http://investigacion.utmachala.edu.ec/proceedings/index.php/utmach/article/view/272/222
Moreno, A., Rigoberto, G., García González, C., & Montes de Oca, J. (2017). ANÁLISIS ECOSISTÉMICO-SUSTENTABLE DE UNA BIOFÁ- BRICA DE VITROPLANTAS EN PREDIOS AGRÍCOLAS DE LA UTMACH, ECUADOR. Revista Científica Agroecosistemas, 5(1-Ext), 140–149. Retrieved fromhttps://aes.ucf.edu.cu/index.php/aes/article/view/151/185
García González, C.,Tene Japon, Alex, Burgos Diaz, Karina & Zambrano, C. (2017). TECNICAS Y METODOS ELECTROMECANICOS: GALVANOPLASTIA Y POTENCIOMETRIA. Revista Científica Alternativashttp://editorial.ucsg.edu.ec/ojs-alternativas/index.php/alternativas-ucsg
García González, C.,Rojas Angulo, Rosa, Neira Quezada,Celinda & Espinoza Pluas, Gerardo. (2017). "DETECCION ESPECTROFOTOMETRICA Y CUANTIFICACION DE ACIDO ACETIL SALICILICO EN FARMACOS",. Revista Científica Alternativashttp://editorial.ucsg.edu.ec/ojs-alternativas/index.php/alternativas-ucsg
M.I. García Pomar, D. Báez Bernal, C. Gilsanz Rey, V. García Souto. Mejora de la eficiencia de la fertilización nitrogenada en los cultivos forrajeros, Vaca Pinta, Volumen 2, Marzo 2018, Páginas 116-126, ISSN: 2603-8080.
Notas
Moreno Herrera, A., García Batista, R. G., García, C., & Montes de Oca Suárez, J. L. (2017). Análisis ecosistémicosustentable de una Biofábrica de vitroplantas en predios agrícolas de la UTMACH, Ecuador.Revista CientíficaAgroecosistemas, 5(1-Ext), 140-149. Recuperado de http://aes.ucf.edu.cu/index.php/aes/index
Otras publicaciones
Jorge M. Blanco Ballón, Miguel Fernández Pardo, Ignacio García Presedo, Juan Fernando Castro Ínsua, Mª Dolores Báez Bernal, Mª Isabel García Pomar, Valentín García Souto. Manual para unha axeitada xestión dos xurros de porcino na Reserva de Biosfera Mariñas Coruñesas e Terras do Mandeo, Noviembre 2017.
Artículos en revistas internacionales
Silvar, C., & García-gonzález, C. A. (2017). Scientia Horticulturae Screening old peppers ( Capsicum spp .) for disease resistance and pungency-related traits. Scientia Horticulturae, 218, 249–257. https://doi.org/10.1016/j.scienta.2017.02.037
García, C., Llanos, M., Mazón, B., Dávila, K., & Cun, J. (2016). CAPSICUM ANNUUM POR VOLTAMETRÍA DE BARRIDO LINEAL DETERMINATION OF VITAMIN C IN PEPPERS CAPSICUM. Revista de Investigación Talentos, 3(2), 1–9. Retrieved from http://www.ueb.edu.ec/app/talentos/index.php/2-uncategorised/56-determinacion-de-vitamina-c-en-pimiento-capsicum-annuum-por-voltametria-de-barrido-lineal
Fernández-Puente P, Calamia V, González-Rodríguez L, Lourido L, Camacho-Encina M, Oreiro N, Ruiz-Romero C, Blanco FJ. Multiplexed mass spectrometry monitoring of biomarker candidates for osteoarthritis. Journal of Proteomics 2016, doi: 10.1016/j.jprot.2016.11.012 
Fernández-Naveira, Á., Veiga, M.C., Kennes, C., 2017. Production of chemicals from C1 gases (CO, CO2) by Clostridium carboxidivorans. World J Microbiol Biotechnol 33:43
Fernández-Naveira, Á., Veiga, M.C., Kennes, C., 2017. H-B-E (hexanol-butanol-ethanol) fermentation for the production of higher alcohols from syngas/waste gas. J Chem Technol Biotechnol 92(4):712-731
Fernández-Naveira, Á., Veiga, M.C., Kennes, C., 2017. Effect of pH control on the anaerobic H-B-E fermentation of syngas in bioreactors. Journal of Chemical Technology and Biotechnology 92:1178-1185
Lagoa-Costa, B., Abubackar, H. N., Fernández-Romasanta, M., Kennes, C., Veiga, M.C., 2017. Integrated bioconversion of syngas into bioethanol and biopolymers. Bioresource Technology 239: 244-249
González Porto SA, González Rodríguez A, Villamarín Bello N, del Pozo Losada J. Láser de dióxido de carbono fraccionado asociado a corticoide tópico para el tratamiento del prurito en las secuelas cicatriciales del paciente quemado. Cir. plást iberolatinoam. 2017 Mar; 43(1):69-75
Rojas S, Pérez Del Caz MD, Esteban Vico JR, Villaverde E, Llinas A, Martínez JR, et al. EHTIC study: Evaluation of a new hemostatic agent based on tissue factor in skin grafting procedures. Burns. 2017 Jun;43(4):780–8 
Ánxela Fernández-Naveira, María C. Veiga and Christian Kennes (2017). Glucose bioconversion profile in the syngas-metabolizing species Clostridium carboxidivorans. Bioresourc Technology 244:552-559
P. Escudero-Rivera1,*, S. Seoane-López1, Sánchez-Fernández, L.R.1, J.R. Pérez-Prado1, M.C. Fernández-Feal1, Analytical simulation of vegetable oil transformation into biodiesel as a preliminary step towards the development of a mathematical model to predict CFPP, pp. 34-39. España: 24/07/2017. ISBN 978-84-697-4339-3.
Artículos en revistas nacionales
Hombreiro L. (2014) La Base de Datos Nacional de Perfiles Genéticos: Regulación, funcionamiento y operatividad. Boletín Gallego de Medicina Legal y Forense nº 20 (enero 2014): 33-41.
Hombreiro L, (2015). Predicción de rasgos físicos, médicos, conductuales y de origen biogeográficoGen-T Septiembre 2015: 109-118.
Artículos en revistas internacionales
Fernández-Naveira A, Abubackar HN, Veiga MC, Kennes C (2016) Efficient butanol-ethanol (B-E) production from carbon monoxide fermentation in Clostridium carboxidivorans. Appl Microbiol Biotechnol doi: 10.1007/s00253-015-7238-1.
Fernández-Naveira, Á., Abubackar, H., Veiga, MC., Kennes, C. 2016. Carbon monoxide bioconversion to butanol-ethanol by Clostridium carboxidivorans: kinetics and toxicity of alcohols. Appl. Microbiol. and Biotechnol. 100:4231–4240 DOI 10.1007/s00253-016-7389-8
Pacheco Compaña FJ, Avellaneda Oviedo EM, González Rodríguez A, González Porto SA. Burn patients during the Summer Solstice festivities: A retrospective analysis in a hospital burn unit from 2005 to 2015. Burns J Int Soc Burn Inj. 2016 May 3
González Porto SA, González Rodríguez A, Midón Míguez J. Intraneural Venous Malformations of the Median Nerve. Arch Plast Surg. 2016 Jul;43(4):371-3
GHEP-ISFG collaborative exercise on mixture profiles of autosomal STRs (GHEP-MIX01, GHEP-MIX02 and GHEP-MIX03): Results and evaluation. Forensic Science International: Genetics 10 (2014) 64-72
Euroforgen-NoE collaborative exercise on LRmix to demonstrate standardization of the interpretation of complex DNA profiles. Forensic Science International: Genetics 9 (2014) 47–54
Ayala Armijos, H., García González, C., Sánchez Prado, R., Jirón Vélez, Y., & Espinoza Ramón, W. (2016). Efecto de la adición de ácido ascórbico en la degradación de nitratos y nitritos en mortadela. CIENCIA UNEMI, Universidad Estatal de Milagro9(20). Retrieved from http://ojs.unemi.edu.ec/index.php/cienciaunemi/index
Artículo aceptado para publicaciónLa revista Cumbres, medio de divulgación académico y científico del Centro de Investigaciones de la Universidad Técnica de Máchala, certifica que el artículo titulado "Cuantificación de ácido ascórbico en pimientos comercializados en la zona 7 del Ecuador aplicando voltamperometría "; ha sido aceptado para su publicación en el volumen 3, número 2, correspondiente al año 2017.http://investigacion.utmachala.edu.ec/revistas/
Ayala et al., 2016. Efecto de la adición de ácido ascórbico y degradación de nitratos y nitritos en mortadela. Ciencia UNEMI 85 - 92.
Artículos en revistas nacionales
Hombreiro L, (2014) Análisis de restos biológicos depositados sobre superficies complejas. Epitelios humanos y elementos balísticos.Boletín Gallego de Medicina Legal y Forense, Vol nº 20 (enero 2014): 61-72
Hombreiro L. (2014). Recogida de restos epiteliales sobre diferentes superficies: eficiencia de la analítica de ADN en casos realesBoletín Gallego de Medicina Legal y Forense. Vol. nº 20 (enero 2014): 73-85
Hombreiro LEstudio descriptivo de los factores de contaminación en las tomas forenses de muestras de ADN. Cuadernos de Medicina Forense 2015;21(3-4)
Hombreiro L, Retrato Robot GenéticoQuadernos de Criminología, Núm. 32 (enero/marzo 2016): 3-9
Libro
El ADN de Locard. Genética Forense y Criminalística. Editorial REUS, 2013.ISBN  978-84-290-1742-7Depósito Legal    M 17291-2013
Garcia, C., Ayala, H., Martinez, O. (2016). Quimica Organica. Editorial UTMACH.
García, C., Jaramillo, C., & Campoverde, J. (2015). Control de Calidad de los Medicamentos Volumen I (1st ed.). Machala: Universidad Técnica de Machala. Retrieved from http://repositorio.utmachala.edu.ec/handle/48000/6656
Artículos en revistas internacionales
Silvar, C., & García-González, C. A. (2016). Deciphering Genetic Diversity in the Origins of Pepper ( spp.) and Comparison with Worldwide Variability. Crop Science, 56, 12. http://doi.org/10.2135/cropsci2016.02.0128
Libro
García González, José Ayala Armijos, O. M. M. (2015). Química Inorgánica (Primera Ed). Machala: Universidad Técnica de Machala.

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